IN VITRO ACTIVITY OF BEDAQUILINE AGAINST NON-TUBERCULOUS MYCOBACTERIA
نویسندگان
چکیده
منابع مشابه
In vitro activity of bedaquiline against rapidly growing nontuberculous mycobacteria
Bedaquiline (BDQ) has been proven to be effective in the treatment of multidrug-resistant tuberculosis. We hypothesized that BDQ could be a potential agent to treat nontuberculous mycobacterial (NTM) infection. The objective of this study was to evaluate the in vitro activity of BDQ against rapidly growing mycobacteria by assessing the minimal inhibitory concentration (MIC) and minimal bacteric...
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BACKGROUND Non-tuberculous mycobacteria (NTM) are ubiquitous environmental organisms. Patients with pre-existing lung damage are susceptible to NTM, but their prevalence in bronchiectasis is unknown. Distinguishing between lung colonisation and disease can be difficult. METHODS A prospective study of 100 patients with bronchiectasis was undertaken to evaluate the prevalence of NTM in sputum, ...
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Chronic airway infection is a key aspect of the pathogenesis of bronchiectasis. A growing interest has been raised on non-tuberculous mycobacteria (NTM) infection. We aimed at describing the clinical characteristics, diagnostic process, therapeutic options and outcomes of bronchiectasis patients with pulmonary NTM (pNTM) disease. This was a prospective, observational study enrolling 261 adult b...
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ژورنال
عنوان ژورنال: Russian Journal of Infection and Immunity
سال: 2019
ISSN: 2313-7398,2220-7619
DOI: 10.15789/2220-7619-2018-4-6.52